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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF4EBP1
All Species:
9.09
Human Site:
T18
Identified Species:
20
UniProt:
Q13541
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13541
NP_004086.1
118
12580
T18
P
S
R
A
I
P
A
T
R
R
V
V
L
G
D
Chimpanzee
Pan troglodytes
XP_001136348
133
14823
V31
R
T
I
P
T
R
T
V
A
I
S
D
A
A
Q
Rhesus Macaque
Macaca mulatta
XP_001091933
141
14878
T18
P
S
R
A
I
P
A
T
R
R
V
V
L
G
D
Dog
Lupus familis
XP_549448
118
12523
T18
P
S
R
A
I
P
A
T
R
R
V
V
L
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q60876
117
12306
R18
P
S
R
A
I
P
T
R
R
V
A
L
G
D
G
Rat
Rattus norvegicus
Q62622
117
12385
R18
P
S
R
A
I
P
T
R
R
V
A
L
G
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514570
67
7606
Chicken
Gallus gallus
XP_424384
116
12481
P18
P
S
R
D
I
P
G
P
G
K
R
L
A
L
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q98TT6
112
12513
P14
Q
S
K
S
C
P
I
P
T
R
V
L
H
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120078
115
12648
P17
A
T
Q
S
Q
N
I
P
S
K
R
I
V
I
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001077103
113
12005
R14
S
R
Q
L
S
A
G
R
D
I
P
S
K
R
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.6
75.8
94.9
N.A.
90.6
92.3
N.A.
44.9
66
N.A.
56.7
N.A.
N.A.
47.4
N.A.
52.5
Protein Similarity:
100
59.4
80.1
97.4
N.A.
94
95.7
N.A.
49.1
76.2
N.A.
67.8
N.A.
N.A.
65.2
N.A.
66.1
P-Site Identity:
100
0
100
100
N.A.
46.6
46.6
N.A.
0
33.3
N.A.
26.6
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
6.6
100
100
N.A.
53.3
53.3
N.A.
0
46.6
N.A.
46.6
N.A.
N.A.
46.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
46
0
10
28
0
10
0
19
0
19
10
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
10
0
0
10
0
19
28
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
19
0
10
0
0
0
19
28
19
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
10
0
55
0
19
0
0
19
0
10
0
10
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
19
0
0
10
0
10
% K
% Leu:
0
0
0
10
0
0
0
0
0
0
0
37
28
19
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% N
% Pro:
55
0
0
10
0
64
0
28
0
0
10
0
0
0
10
% P
% Gln:
10
0
19
0
10
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
10
10
55
0
0
10
0
28
46
37
19
0
0
10
0
% R
% Ser:
10
64
0
19
10
0
0
0
10
0
10
10
0
0
0
% S
% Thr:
0
19
0
0
10
0
28
28
10
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
10
0
19
37
28
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _